BARRETT, STEPHEN DOUGLAS,COLOMBO, JOSEPH MICHAEL,GERMAIN, BRADLEE DAVID,ENDRES, GREGORY WILLIAM,KORNILOV, ANDRIY,KRAMER, JAMES BERNARD,UZIEBLO, ADAM,CISKE, FRED LAWRENCE,MAXEY, KIRK M.,O'MALLEY, JAMES
申请号：
CA2906134
公开号：
CA2906134A1
申请日:
2014.03.14
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
Disclosed herein are compounds of formula (I) wherein L1,L2, L3, L4, R1, R4, R5, R6, and s are as defined in the specification.Compounds of formula (I) are EP4 agonists useful in the treatment of glaucoma,osteoporosis, bone fracture, periodontal bone loss, orthopedic implant,alopecia,neuropathic pain, and related disorders. Pharmaceutical compositionsand methods of treating conditions or disorders are also described.
