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LACTAM COMPOUNDS AS EP4 RECEPTOR-SELECTIVE AGONISTS FOR USE IN THE TREATMENT OF EP4-MEDIATED DISEASES AND CONDITIONS
专利权人:
MYOMETRICS LLC;CAYMAN CHEMICAL COMPANY; INC.;CAYMAN CHEMICAL COMPANY, INC.
发明人:
BARRETT, STEPHEN, DOUGLAS,COLOMBO, JOSEPH, MICHAEL,GERMAIN, BRADLEE, DAVID,ENDRES, GREGORY, WILLIAM,KORNILOV, ANDRIY,KRAMER, JAMES, BERNARD,UZIEBLO, ADAM,CISKE, FRED, LAWRENCE,MAXEY, KIRK, M.,O'MALLEY,OMALLEY,
申请号:
SG11201507470W
公开号:
SG11201507470WA
申请日:
2014.03.14
申请国别(地区):
SG
年份:
2015
代理人:
摘要:
Disclosed herein are compounds of formula (I) wherein L 1 , L 2 , L 3 , L 4 , R 1 , R 4 , R 5 , R 6 , and s are as defined in the specification. Compounds of formula (I) are EP 4 agonists useful in the treatment of glaucoma, osteoporosis, bone fracture, periodontal bone loss, orthopedic implant, alopecia, neuropathic pain, and related disorders. Pharmaceutical compositions and methods of treating conditions or disorders are also described.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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