ROQUE NAVARRO LOUDES TATIANA,ROQUE NAVARRO Loudes Tatiana,MATEO DE ACOSTA DEL RIO CRISTINA MARIA,MATEO DE ACOSTA DEL RIO Cristina Maria,RODRIGUEZ GONZALEZ MABEL CONSEJAL VEIGA NO 110,RODRIGUEZ GONZALE
申请号：
SI200432242
公开号：
SI1623997T1
申请日:
2004.04.22
申请国别(地区):
SI
年份:
2015
代理人:
摘要：
The invention essentially relates to the production of less immunogenic immunoglobulins by means of genetic engineering and, more specifically, to a monoclonal antibody recognizing antigens which contain the N-glycolil GM3 ganglioside but not other gangliosides of the N-glycolil or N-acetyl type, or the sulphated glycolipids. In particular the invention relates to peptides sequences encoding a recombinant monoclonal antibody against the N-glycolil GM3 ganglioside, or derivative fragments of the same. The invention further relates to pharmaceutical compositions containing the aforementioned antibody or fragments thereof and to the diagnostic or therapeutic use of same for breast cancer and melanoma.
