BARBARA A. SWANSON,GUNNAR F. KAUFMANN,HEYUE ZHOU,JOHN DIXON GRAY,RANDY GASTWIRT
申请号：
BR112014029883
公开号：
BR112014029883A2
申请日:
2013.05.31
申请国别(地区):
BR
年份:
2017
代理人:
摘要：
There is disclosed compositions and methods relating to or derived from anti-PD-Ll antibodies. More specifically, there is disclosed fully human antibodies that bind PD-L1, PD-L1-binding fragments and derivatives of such antibodies, and PD-L1-binding polypeptides comprising such fragments. Further still, there is disclosed nucleic acids encoding such antibodies, antibody fragments and derivatives and polypeptides, cells comprising such polynucleotides, methods of making such antibodies, antibody fragments and derivatives and polypeptides, and methods of using such antibodies, antibody fragments and derivatives and polypeptides, including methods of treating or diagnosing subjects having PD-L1 related disorders or conditions, including various inflammatory disorders and various cancers.
