MAZDIYASNI HORMOZ,PETTER RUSSELL,TESTER RICHLAND WAYNE,NIU DEQIANG,KLUGE ARTHUR F.,QIAO LIXIN,SINGH JUSWINDER,WESTLIN III WILLIAM FREDERICK
申请号：
NZ70023610
公开号：
NZ700236A
申请日:
2010.12.29
申请国别(地区):
NZ
年份:
2016
代理人:
摘要：
Disclosed herein are pyrimidine substituted compounds of general formulae I-a & I-b, processes for their preparation, compositions comprising said compounds and uses thereof. Said compounds are useful as inhibitors of protein kinase, particularly BTK, JAK3 and TEC-kinase and as such are useful in the treatment of autoimmune disease, heretoimmune disease, inflammatory disease, cancer, disease of the bone and joints, a thromboembolic disorder, a neurodegenerative disorder, or a solid or hematologic malignancy.
