SASS, PHILIP M.,NICOLAIDES, NICHOLAS E.,GRASSO, LUIGI,LI, JIAN,CHAO, QIMIN,ROUTHIER, ERIC,EBEL, WOLFGANG
申请号：
CA2641169
公开号：
CA2641169C
申请日:
2007.02.08
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
Hybridoma lines that secrete human monoclonal antibodies with high bindingspecificity and biological activity, particularly neutralizing activityagainst granulocyte-macrophage colony stimulating factor, and methods ofgenerating the hybridoma lines are provided. Target antigens and epitopes arealso provided. The antibodies may be used in therapeutic methods, for examplein the treatment of cancer, infectious disease, or autoimmune disease.
