SASS, PHILIP M.,NICOLAIDES, NICHOLAS E.,GRASSO, LUIGI,LI, JIAN,CHAO, QIMIN,ROUTHIER, ERIC,EBEL, WOLFGANG
申请号：
CA2961031
公开号：
CA2961031C
申请日:
2007.02.08
申请国别(地区):
CA
年份:
2020
代理人:
摘要：
Hybridoma lines that secrete human monoclonal antibodies with high binding specificity and biological activity, particularly neutralizing activity against granulocyte-macrophage colony stimulating factor, and methods of generating the hybridoma lines are provided. Target antigens and epitopes are also provided. The antibodies may be used in therapeutic methods, for example in the treatment of cancer, infectious disease, or autoimmune disease.
