Ajit Narang,Venkatramana M. Rao,Divyakant S. Desai
申请号：
US13820330
公开号：
US20130224296A1
申请日:
2011.09.01
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The present invention relates to solid, semisolid, or liquid formulations comprising water soluble antioxidants that prevent or reduce formic acid and/or formyl species generation in the dosage form during the manufacturing process and/or during shelf-life storage. The formulations of the present invention prevent or reduce formation of N-formyl impurities (and gelatin cross-linking) during the manufacturing process and/or during shelf-life storage.
