A device for performing skin treatments which includes a cartridge having a compartment for holding a treatment fluid and a reservoir for receiving a waste fluid, both of which are in communication with a source of vacuum pressure. The vacuum source withdraws the treatment fluid through an outlet in an applicator head and then draws used fluid into the waste reservoir. The applicator head can include an abrasive material for performing microdermabrasion and/or an anode and cathode for applying microcurrents.