The Board of Trustees of the University of Illinois
发明人:
BURKE, Martin, D.,GRILLO, Anthony, S.
申请号:
EP16735544
公开号:
EP3242723A4
申请日:
2016.01.11
申请国别(地区):
EP
年份:
2018
代理人:
摘要:
Provided are methods of treating a disease or condition characterized by a deficiency of or a defect in an iron transporter using a small molecule. For example, the method may increase transepithelial iron transport, or it may increase iron release. Additionally, the small molecule may be hinokitiol, or it may be selected from the group consisting of amphotericin B, calcimycin, nonactin, deferiprone, purpurogallin, and maltol. Also provided is a method of identifying a compound capable of treating a disease or condition characterized by a deficiency of or a defect in an iron transporter.