KUCHERLAPATI, RAJU,JAKOBOVITS, AYA,KLAPHOLZ, SUE,BRENNER, DANIEL G.,CAPON, DANIEL J.
申请号：
CA2219361
公开号：
CA2219361C
申请日:
1996.04.29
申请国别(地区):
CA
年份:
2012
代理人:
摘要：
Fully human antibodies against a specific antigen can be prepared byadministering the antigen to a transgenic animal which has been modified toproduce such antibodies in response to antigenic challenge, but whoseendogenous loci have been disabled. Various subsequent manipulations can beperformed to obtain either antibodies per se or analogs thereof.
