An apparatus for delivery of a substance to an anatomical region in a body caninclude a cathetercomprising a catheter body, and one or more electrically conductive elementssupported by thecatheter body and in electrical communication with one or more sources ofelectrical stimulus.The catheter body can comprise a lumen therein, a substantially closed distalend, and an infusionsection configured to permit fluid to pass through the catheter body and thatcan have a lengththat is less than or equal to the length of the catheter body. In someembodiments, the apparatuscan comprise a coiled member positioned within the lumen of the catheter body.The coiledmember can comprise adjacent coils and can permit the uniform flow of thesubstance throughone or more holes formed in the catheter body.