An apparatus for delivery of a substance to an anatomical region in a body can includea catheter comprising a catheter body, and one or more electrically conductiveelements supported by the catheter body and in electrical communication withone or more sources of electrical stimulus. The catheter body can comprise a lumentherein, a substantially closed distal end, and an infusion section configuredto permit fluid to pass through the catheter body and that can have a length thatis less than or equal to the length of the catheter body. In some embodiments, theapparatus can comprise a coiled member positioned within the lumen of the catheterbody. The coiled member can comprise adjacent coils and can permit the uniformflow of the substance through one or more holes formed in the catheter body.