KESSLER, THOMAS,BREITENBACH, JOERG,SCHMIDT, CHRISTOPH,DEGENHARDT, MATTHIAS,ROSENBERG, JOERG,KRULL, HARALD
申请号：
CA2644035
公开号：
CA2644035C
申请日:
2007.03.12
申请国别(地区):
CA
年份:
2013
代理人:
摘要：
A process for producing a solid dispersion of an active ingredient which comprises feeding the active ingredient and a matrix-forming agent to an extruder and forming a uniform extrudate, wherein the extruder comprises at least two rotating shafts (2), each of the shafts (2) carrying a plurality of processing elements disposed axially one behind the other, the processing elements defining (i) a feeding and conveying section (A), (ii) at least one mixing section (B), and (iii) a discharging section (E), wherein the processing element(s) defining the mixing section (B) comprise(s) a mixing element (11, 12, 13) that is derived from a screw type element (figure 2).
