A solution to prevent the spread of Clostridium difficile in a health care facility comprises 3-(trihydroxysilyl) propyldimethyloctadecyl ammonium chloride and either peracetic acid or hydrogen peroxide, or a combination of both peracetic acid and hydrogen peroxide. The 3-(trihydroxysilyl) propyldimethyloctadecyl ammonium chloride can be between 0.10 percent and 10 percent by weight of the solution. The peracetic acid can be between 0.10 percent and 10 percent by weight of the solution. The hydrogen peroxide can be between 1 percent and 10 percent by weight of the solution. A method of preventing the spread of Clostridium difficile in a health care facility comprises entering a room in said facility that has a surface where Clostridium difficile is present and applying said solution.
