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含有抗體之液體製劑
专利权人:
LTD.;MOCHIDA PHARMACEUTICAL CO.
发明人:
OKUWAKI, RYO,奥脇龙,奧脇龍
申请号:
TW106110578
公开号:
TW201836637A
申请日:
2017.03.29
申请国别(地区):
TW
年份:
2018
代理人:
摘要:
Provided is a recombinant monoclonal antibody-containing liquid pharmaceutical agent which can realize the stability of dimer formation inhibition and deamidation inhibition during long-term storage and is suitable for a wide range of antibody concentration. A recombination monoclonal antibody-containing liquid pharmaceutical agent comprises 10 mg/ml ~ 200 mg/ml recombinant monoclonal antibody and 40 mM ~ 94 mM amino acid components having histidine component of less than 5 mM and has a pH value of 5.5 to 7.0. Furthermore, the amino acid components other than the histidine component have at least one component selected from the group consisting of arginine, arginine hydrochloride and methionine.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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