MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
发明人:
Atta Behfar,Andre Terzic
申请号：
US16463053
公开号：
US20190275071A1
申请日:
2017.11.22
申请国别(地区):
US
年份:
2019
代理人:
摘要：
A composition for delivering a biologic to a subject generally includes a particulate substrate and an mRNA encapsulated by the particulate substrate. In some cases, the mRNA bay be indirectly attached to the particulate substrate. The mRNA encodes at least one therapeutic polypeptide. The composition may be delivered to a tissue of a subject to provide a therapeutic benefit to the tissue.
