Department of Veterans Affairs;The University of Utah
发明人:
Bellamkonda K. Kishore,Yue Zhang,Noel G. Carlson
申请号：
US15885435
公开号：
US20180214450A1
申请日:
2018.01.31
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Disclosed are methods for treating kidney disease including autosomal dominant polycystic kidney disease (ADPKD) in a subject, comprising the step of administering to the subject a composition comprising a therapeutically effective amount of ticagrelor or a derivative thereof, thereby treating ADPKD. Disclosed are methods of decreasing arginine vasopressin (AVP) production in a subject comprising the step of administering to the subject a composition comprising an effective amount of ticagrelor, thereby decreasing AVP production. Disclosed are methods for treating dilutional hyponatremia in a subject comprising the step of administering to the subject a composition comprising an effective amount of ticagrelor, thereby decreasing AVP production.
