United States Government As Represented By The Department of Veterans Affairs
发明人:
BELLAMKONDA K. KISHORE,Yue Zhang,Noel G. Carlson
申请号:
US16841098
公开号:
US20200234552A1
申请日:
2020.04.06
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Disclosed are methods for treating kidney disease including autosomal dominant polycystic kidney disease (ADPKD) in a subject, comprising the step of administering to the subject a composition comprising a therapeutically effective amount of ticagrelor or a derivative thereof, thereby treating ADPKD. Disclosed are methods of decreasing arginine vasopressin (AVP) production in a subject comprising the step of administering to the subject a composition comprising an effective amount of ticagrelor, thereby decreasing AVP production. Disclosed are methods for treating dilutional hyponatremia in a subject comprising the step of administering to the subject a composition comprising an effective amount of ticagrelor, thereby decreasing AVP production.