A device for determining the rheological properties of blood may include a channel having at least one channel sub-section that has a substantially constant cross-section; apparatus for determining a pressure differential along at least a portion of the sub-section of the channel; a first reservoir that is adapted to be located at a first end of the channel and to be placed in fluid communication with the channel, the first reservoir being of variable internal volume; a second reservoir that is adapted to be placed in fluid communication with first reservoir via the channel, the second reservoir being of variable internal volume; means for allowing blood to be introduced into the device; an outlet for allowing gas to be expelled from the device; and means for varying the volume of the first reservoir.