DENGUE TETRAVALENT VACCINE CONTAINING A COMMON 30 NUCLEOTIDE DELETION IN THE 3'-UTR OF DENGUE TYPES 1, 2, 3, AND 4, OR ANTIGENIC CHIMERIC DENGUE VIRUSES 1, 2, 3, AND 4
The United States of America;Department of Health and Human Service;as represented by the Secretary
发明人:
Stephen S. Whitehead,Brian R. Murphy,Lewis Markoff,Barry Falgout,Joseph Blaney,Kathryn Hanley,Ching-Juh Lai
申请号:
US15710672
公开号:
US20180010099A1
申请日:
2017.09.20
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The invention relates to a dengue virus tetravalent vaccine containing a common 30 nucleotide deletion (Δ30) in the 3′-untranslated region of the genome of dengue virus serotypes 1, 2, 3, and 4, or antigenic chimeric dengue viruses of serotypes 1, 2, 3, and 4.