Dengue tetravalent vaccine containing a common 30 nucleotide deletion in the 3′-UTR of dengue types 1, 2, 3, and 4, or antigenic chimeric dengue viruses 1, 2, 3, and 4
Lewis Markoff;Brian R. Murphy;Joseph Blaney;Ching-Juh Lai;Stephen S. Whitehead;Barry Falgout;Kathryn Hanley
发明人:
Stephen S. Whitehead,Brian R. Murphy,Lewis Markoff,Barry Falgout,Joseph Blaney,Kathryn Hanley,Ching-Juh Lai
申请号:
US13305639
公开号:
US09783787B2
申请日:
2011.11.28
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The invention relates to a dengue virus tetravalent vaccine containing a common 30 nucleotide deletion (Δ30) in the 3′-untranslated region of the genome of dengue virus serotypes 1, 2, 3, and 4, or antigenic chimeric dengue viruses of serotypes 1, 2, 3, and 4.