Dengue tetravalent vaccine containing a common 30 nucleotide deletion in the 3′-UTR of dengue types 1,2,3, and 4, or antigenic chimeric dengue viruses 1,2,3, and 4
The United States of America; as represented by the Secretary; Department of Health & Human Services
发明人:
Stephen S. Whitehead,Brian R. Murphy,Lewis Markoff,Barry Falgout,Joseph E. Blaney,Kathryn A. Hanley,Ching-Juh Lai
申请号:
US13896388
公开号:
USRE046641E1
申请日:
2013.05.17
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The invention relates to a dengue virus tetravalent vaccine containing a common 30 nucleotide deletion (Δ30) in the 3′-untranslated region of the genome of dengue virus serotypes 1, 2, 3, and 4, or antigenic chimeric dengue viruses of serotypes 1, 2, 3, and 4.