Stuart A. Forman;Syed S. Husain;Gregory D. Cuny;Joseph F. Cotten;Douglas E. Raines;Keith W. Miller
发明人:
Douglas E. Raines,Joseph F. Cotten,Stuart A. Forman,Keith W. Miller,Syed S. Husain,Gregory D. Cuny
申请号：
US13382544
公开号：
US08765973B2
申请日:
2010.07.08
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The invention is directed to compounds according to formula (I): where R1 is L1C(O)OT or L1C(O)OL2C(O)OT； R2 is a substituted or unsubstituted C1-C10 alkyl, C2-C10 alkenyl, or C2-C10 alkynyl, or R1； n is an integer from 0 to 5； each R3 is independently halogen or R2； R4 and R5 are independently H, halogen, CN or CF3； L1 and L2 are each independently a bond, a substituted or unsubstituted C1-C10 alkylene, C2-C10 alkenylene, or C2-C10 alkynylene； and T is H, a substituted or unsubstituted C1-C10 alkyl, C2-C10 alkenyl, or C2-C10 alkynyl, nitrophenol, or cyclopropyl. The invention is also directed to a pharmaceutical composition comprising a compound according to formula (I) and a pharmaceutically acceptable carrier, and to methods for providing anesthesia in mammals by administering such a pharmaceutical composition.
