The present invention relates to [1,2,4]triazolo[4,3-a]pyridine derivatives, the preparation method and medical use thereof. Specifically, the present invention relates to a [1,2,4]triazolo[4,3-a]pyridine derivative represented by formula (I), a preparation method thereof, a pharmaceutical composition containing the same, a use as a therapeutic agent especially as a c-Met inhibitor and an immunosupressant, wherein all substituents of formula (I) are defined as those in the specification.本發明涉及[1,2,4]三唑並[4,3-a]吡啶類衍生物,其製備方法或其在醫藥上的應用。具體而言,本發明涉及一種如通式(I)所示的[1,2,4]三唑並[4,3-a]吡啶類衍生物,其製備方法及含有該衍生物的醫藥組成物以或其作為治療劑,特別是作為c-Met抑制劑和免疫抑制劑的用途,其中通式(I)的各取代基與說明書中的定義相同。
