Imidazolidine simultaneously [1,5-a] Pyrazine derivative, preparation method and its application in medicine农业专利-农业专业知识服务系统

专利权人:: 上海恒瑞医药有限公司; LTD.;上海恒瑞醫藥有限公司;SHANGHAI HENGRUI PHARMACEUTICAL CO.;江蘇恒瑞醫藥股份有限公司;SHANGHAI HENGRUI PHARMACEUTICAL CO., LTD.;JIANGSU HENGRUI MEDICINE CO., LTD.;江苏恒瑞医药股份有限公司

发明人:: TANG, Peng Cho,邓炳初,鄧炳初,YANG, Fanglong,杨方龙,楊方龍,FAN, Jiang,范江,FENG, Hu,冯虎,馮虎,WANG, Yang,王阳,王陽,YANG, Tao,杨韬,楊韜

摘要：: The present invention relates to imidazolidine shown in a kind of logical formula (I) simultaneously [1,5-a] Pyrazine derivative, preparation method and pharmaceutical composition containing the derivative as well as therapeutic agent are especially as the purposes of inhibitors of dipeptidyl IV, and definition is the same as that in the specification for each substituent group in formula of (I).本發明涉及一種通式(I)所示的四氫咪唑并[1,5-a]吡嗪類衍生物、其製備方法以及含有該衍生物的藥物組合物、以及其作爲治療劑特別是作爲二肽基肽酶IV抑制劑的用途，其中通式(I)中的各取代基的定義與說明書中的定義相同。