Maria Clementine Martin Klosterfrau Vertriebsgesellschaft mbH
发明人:
NAUERT, Christian,GREVE, Harald
申请号:
ES11773680
公开号:
ES2588741T3
申请日:
2011.10.11
申请国别(地区):
ES
年份:
2016
代理人:
摘要:
Process for the preparation of a composition at least essentially free of alcohol based on at least one plant extract with secreolytic and / or expectoration promoting effect, the composition having an alcohol content, in particular an ethanol content, less than 2 % in vol., wherein the procedure comprises the following process steps: (a) provision of at least one alcoholic plant extract, in particular ethanol with a secreolytic and / or expectoration promoting effect with a drug / extract ratio in the range from 1: 10 to 10: 1, where the at least one plant extract with secreolytic and / or expectoration effect is chosen from the group of thyme extract (Thymus vulgaris), primrose root extract (Primula), extract Ivy (Hedera helix), elderberry extract (Sambucus nigra), fennel extract (Foeniculum vulgare), Tusilago extract (Tussilago farfara), Anise extract (Pimpinella anis um) and polypodium extract (Polypodium vulgare), as well as mixtures and combinations of at least two of the aforementioned extracts and (b) subsequent separation of alcohol, in particular from ethanol, by membrane filtration to obtain an essentially free composition of alcohol with an alcohol content, in particular an ethanol content, of less than 2% in vol., based on at least one plant extract with secreolytic and / or expectoration-promoting effect, where before carrying out the membrane filtration at least one dispersing or wetting agent is added, preferably a solubilizer, and / or wherein the membrane filtration is carried out in the presence of at least one dispersing or wetting agent, preferably a solubilizer, the dispersing agent being chosen or humectant of the group of oils, fats and organic fatty acids, lecithins, glycerides, as well as their combinations, and wherein the dispersing or wetting agent is used in amounts of 0.1 to 30% by weight, based on the total mixture to be subjected to membrane filtration based on alcoholic vegetable extract, additive, water and, eventually, other const