MARLOW ALLISON L,WALLACE ELI,SEO JEONGBEOB,LYSSIKATOS JOSEPH P,YANG HONG WOON,BLAKE JIM
申请号：
ZA200807628
公开号：
ZA200807628B
申请日:
2008.09.04
申请国别(地区):
ZA
年份:
2013
代理人:
摘要：
Disclosed are compounds of the Formula I and pharmaceutically acceptable salts and prodrugs thereof, wherein R 1 , R 2 , R 7 , R 8 and R 9 , W, X and Y are as defined in the specification. Such compounds are MEK inhibitors and useful in the treatment of hyperproliferative diseases, such as cancer and inflammation, in mammals, and inflammatory conditions. Also disclosed are methods of using such compounds in the treatment of hyperproliferative diseases in mammals and pharmaceutical compositions containing such compounds.
