Eli M. Wallace;Hong-Woon Yang;Jeongbeob Seo;Joseph P. Lyssikatos;Allison L. Marlow;James F. Blake
发明人:
James F. Blake,Joseph P. Lyssikatos,Allison L. Marlow,Jeongbeob Seo,Eli M. Wallace,Hong-Woon Yang
申请号：
US12356428
公开号：
US08211921B2
申请日:
2009.01.20
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Disclosed are compounds of the Formulaand pharmaceutically acceptable salts and prodrugs thereof, wherein R1, R2, R7, R8, R9, W, and X are as defined in the specification. Such compounds are MEK inhibitors and useful in the treatment of hyperproliferative diseases, such as cancer and inflammation, in mammals, and inflammatory conditions. Also disclosed are methods of using such compounds in the treatment of hyperproliferative diseases in mammals and pharmaceutical compositions containing such compounds.
