Michelle R. Machacek,Michael D. Altman,Eric T. Romeo,Dilrukshi Vitharana,Brandon Cash,Tony Siu,Hua Zhou,Matthew Christopher,Solomon D. Kattar,Andrew M. Haidle,Kaleen Konrad Childers,Matthew L. Maddess
申请号:
US14409133
公开号:
US09242984B2
申请日:
2013.06.18
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention provides novel pyrazole derivatives of formula I which are potent inhibitors of spleen tyrosine kinase, and are useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, COPD, rheumatoid arthritis, and cancer.