DERIVES DE TRIAZOLO- ET TETRAZOLOPYRIMIDINE EN TANT QU'INHIBITEURS DE L'ELASTASE NEUTROPHILE HUMAINE (HNE) POUR LE TRAITEMENT DE LA MALADIE PULMONAIRE OBSTRUCTIVE CHRONIQUE (COPD)
VON NUSSBAUM, FRANZ,KARTHAUS, DAGMAR,ANLAUF, SONJA,DELBECK, MARTINA,LI, VOLKHART MIN-JIAN,MEIBOM, DANIEL,LUSTIG, KLEMENS
申请号:
CA2749040
公开号:
CA2749040C
申请日:
2009.12.29
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
The present invention relates to compounds of the formula (I):(see formula I)wherein A, Y, Z, and R1-R5 are as defined herein, to processes for theirpreparation, to theiruse alone or in combination for the treatment and/or prevention of diseasesarid also to theiruse for preparing medicaments for the treatment and/or prevent of diseases, inparticular forthe treatment and/or prevention of disorders of the lung and thecardiovascular system.