Daohong Zhou,Lijian Shao,Wei Feng,Jianhui Chang,Yingying Wang
申请号:
US15545480
公开号:
US20180021323A1
申请日:
2016.01.22
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention relates to modulators of FLIP protein and their method of use in the treatment and prevention of diseases and pathologies related to accumulation of senescent cells during aging, such as cancer, chronic obstructive pulmonary disease (COPD), osteoarthritis, atherosclerosis, neurodegenerative diseases, diabetes, and many others. The present invention also relates to pharmaceutical compositions containing these compounds as well as various uses thereof.