LINZ KLAUS,ZEMOLKA SASKIA,NOLTE BERT,SCHUNK STEFAN,SCHICK HANS
申请号:
IN211/KOLNP/2013
公开号:
IN2013KN00211A
申请日:
2013.01.24
申请国别(地区):
IN
年份:
2013
代理人:
摘要:
The invention relates to cis-tetrahydro-spirotcyclohexane-1,.1"-pyriclo[3,4-b]indole)-4-amine derivatives which act on the nociceptin/ORL-1 receptor system as well as on the µ-opioid receptor system and which are distinguished in particular by selective effectiveness in the treatment of chronic pain (inter alia inflammatory pain, visceral pain, tumour pain, preferably neuropathic pain) without at the same time developing pronounced effectiveness in the case of acute, nociceptive pain.