LINZ, KLAUS,ZEMOLKA, SASKIA,NOLTE, BERT,SCHUNK, STEFAN,SCHICK, HANS
申请号：
CA2806633
公开号：
CA2806633C
申请日:
2011.07.27
申请国别(地区):
CA
年份:
2019
代理人:
摘要：
The invention relates to cis-tetrahydro-spiro(cyclohexane-1,1-pyrido[3,4-b]indole)-4-aminederivatives which act on the nociceptin/ORL-1 receptor system as well as onthe µ-opioidreceptor system and which are distinguished in particular by selectiveeffectiveness in thetreatment of chronic pain (inter alia inflammatory pain, visceral pain, tumourpain, preferablyneuropathic pain) without at the same time developing pronounced effectivenessin the caseof acute, nociceptive pain.
