Klaus Linz;Bert Nolte;Saskia Zemolka;Stefan Schunk;Hans Schick
发明人:
Klaus Linz,Saskia Zemolka,Bert Nolte,Stefan Schunk,Hans Schick
申请号：
US13192641
公开号：
US20120029006A1
申请日:
2011.07.28
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Cis-tetrahydro-spiro(cyclohexane-1,1′-pyrido[3,4-b]indole)-4-amine compounds which act on the nociceptin/ORL-1 receptor system as well as on the μ-opioid receptor system and which are distinguished in particular by selective effectiveness in the treatment of chronic pain, such as inflammatory pain, visceral pain, tumour pain, and neuropathic pain, without at the same time developing pronounced effectiveness against acute, nociceptive pain.
