NEUROTROPE BIOSCIENCE, INC.;ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
发明人:
IOANNOU, YIANNIS A.,ALTSTIEL, LAWRENCE,CROCKFORD, DAVID R.,KONGSAMUT, SATHAPANA
申请号：
CA2946115
公开号：
CA2946115A1
申请日:
2015.04.14
申请国别(地区):
CA
年份:
2015
代理人:
摘要：
Treating subjects having a lipid storage disorder with a composition comprising a PKC activator, such as bryostatins, bryologs, and polyunsaturated fatty acids. Accordingly, the present disclosure provides methods for treating human subjects suffering from lipid storage disorders, such as Niemann-Pick disease, by administering PKC activators. The present disclosure provides, according to certain embodiments, methods comprising administering to a subject with Niemann-Pick Type C disease a pharmaceutically effective amount of bryostatin 1.
