1. Pyrazole, Isoxazoles, endazoles, endosulfan and pyrdane, and their pharmaceutically acceptable salts, are provided in accordance with the formula (1) described in this document. The report also introduces the drug composition and treatment of grade I hyperoxia (PH) and renal calculi. Claim 1: a compound calculated according to formula (1),a. A ring of a ring is from 1,2,3-thiadiazole-4,5,5,5-methyl-1h-pirazol-3,4-diil (5-methyl) - 1-pyrazol-3, 4-diil (5-methyl) - isothiazole-3, 4-diil (5-methyl) - isothiazole-3, 4-diil (5-methyl) - isothiazole-3, 4-diil, and piridazin-3, 4-diil, 4-diil； n index 0, 0, 0, N, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 (b) W is from − NR ° - n ° -,-C（r3）8322-，-It's just-Yes-S（o）……Y-S（o）8322-；a. Each and each are independent of o-y-c (r83088) 8322 -；R1 consisted of five to six members of halo, Ciano, heterosexual, y-l - (arilo c8333, 18321)； and 8320；a. R74919 was substituted for arilo；Selected from the group composed of H and c.83218831832626；Each R3 cubic meter is selected independently of the asphalt groups h and C 83218331832626；And arilalquilo c832783.3183218383262； 832626；a. Arilalquilo of arilalquilo can replace R3 74919；a. Each r830808 is available from h, c83218833226 and arilalquilo c8327833331 and 8321； lease agreement No. 832626；a. Alternatively, r830880 can be used to replace arilalquilo in arilalquilo；O two r83088 are taken away together to form alquenilo c832183318326；R1 749191 was selected independent of the group consisting of halogenated, cyano-m (isopropyl of 8-12-member),-M - (heterosexual with 5-6 members)-M-（cycloquil C83231；Y-M-（Aril C832683318321；8320）；Selective, heterosexual, r1-955, and heterosexual are substituted；R3 ° 74919 is independent of the group composed of halogen, cyanogen, asphalt and asphalt c831833126；Alcoxi C832188331636262；-M - (non bicycle for 8-12 members)-M - (h
