Motoki TAKAGI,Akira SHIMAMOTO,Yasuhiro FURUICHI,Ayumi SATO
申请号:
US13629226
公开号:
US20130090370A1
申请日:
2012.09.27
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention revealed that by suppressing the expression of the WRN gene, the BLM gene, or the RecQ1 gene, which belong to the RecQ helicase family, apoptosis is induced in various cancer cells and their proliferation is suppressed. Compounds that suppress the expression of RecQ helicase family genes or the functions of RecQ helicase proteins are thought to have the activity of inducing apoptosis.