Elongator Proteins and Use Thereof as DNA Demethylases

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专利权人:

Yi Zhang

发明人:

Yi Zhang,Yuki Okada,ZHANG, Yi,OKADA, Yuki

申请号：

US13499870

公开号：

US20120264811A1

申请日:

2010.10.15

申请国别(地区):

US

年份:

2012

代理人:

摘要：

The invention provides DNA demethylases comprising Elp1, Elp2, Elp3, Elp4, Elp5 and/or Elp6. The invention also provides methods of modulating gene expression, for example, for the treatment of cancer or to modify the cellular transcription program (e.g., for regenerative medicine). Also provided are methods of identifying compounds that modulate the DNA demethylase activity of the DNA demethylases of the invention.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/