UPARAP AIMED ANTI-MEDICINAL CONJUGATES

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专利权人:

РИГШОСПИТАЛЕТ (DK);ЮНИВЕРСИТИ ОФ КОПЕНГАГЕН (DK)

发明人:

НИЛЬСЕН, Кристоффер (DK),БЕХРЕНДТ, Нильс (DK),ЭНГЕЛЬХОЛЬМ, Ларс Хеннинг (DK)

申请号：

RU2018125309

公开号：

RU2018125309A

申请日:

2017.02.03

申请国别(地区):

RU

年份:

2020

代理人:

摘要：

The present invention relates to conjugates targeting uPARAP, in particular antibody-drug conjugates (ADCs) comprising monoclonal antibodies directed against the N-terminal region of uPARAP, and their use in delivery of active agents to cells and tissues expressing uPARAP. The invention further relates to the use of said ADCs in the treatment of diseases involving uPARAP expressing cells, such as cancer.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/