Provided is a solid oral controlled release formulation of lacosamide wherein (a) an amount of about 8.5 wt-% to about 41 wt-% of lacosamide relative to the total lacosamide content of the formulation is released within 1 h, (b) an amount of about 15 wt-% to about 64 wt-% of lacosamide relative to the total lacosamide content of the formulation is released within 2 h, and/or 10 (c) an amount of about 28 wt-% to about 88 wt-% of lacosamide relative to the total lacosamide content of the formulation is released within 4 h, when the in-vitro release of lacosamide is measured according to USP (edition 24) method (711), dissolution apparatus 2, in 900 mL of 0.1 N HCI at 75 rpm. The formulation comprises a lacosamide release controlling agent either in the matrix of the formulation or as a release controlling layer. The formulation is suitable for once daily administration.
