NIELSEN, SIMON FELDBAEK,VIFIAN, THOMAS,HORNEMAN, ANNE MARIE,LAU, JESPER FAERGEMANN
申请号：
NZ59359509
公开号：
NZ593595A
申请日:
2009.12.18
申请国别(地区):
NZ
年份:
2013
代理人:
摘要：
ABSTRACT - 593595 The disclosure relates to triazolopyridine derivatives to formula (I), wherein the variables R1, R2, X, Y and A are as defined in the specification, which exhibit phosphodiesterase PDE4 inhibitory activity and may be used in the treatment of inflammatory diseases or autoimmune diseases, in particular inflammatory or proliferative dermal diseases selected from the group consisting of proliferative and inflammatory skin disorders, psoriasis, cancer, epidermal inflammation, alopecia, skin atrophy, steroid induced skin atrophy, skin ageing, photo skin ageing, acne, dermatitis, atopic dermatitis, seborrheic dermatitis, contact dermatitis, urticaria, pruritis, and eczema.
