PROBLEM TO BE SOLVED: To provide a new compound composition which induces pluripotent stem cells.SOLUTION: There is provided a pluripotent stem cell inducer for inducing cells into pluripotent stem cells, which contains one or more kinds of single-stranded polynucleotides or double-stranded polynucleotides that are selected from the group consisting of: (a) a single-stranded polynucleotide or double-stranded polynucleotide that comprises a specific base sequence or a base sequence that is produced by deleting, substituting or adding one to three bases in the base sequence； (b) a single-stranded polynucleotide or double-stranded polynucleotide that comprises a different specific base sequence or a base sequence that is produced by deleting, substituting or adding one to three bases in the base sequence； and (c) a single-stranded polynucleotide or double-stranded polynucleotide that comprises a further different specific base sequence or a base sequence that is produced by deleting, substituting or adding one to three bases in the base sequence.【課題】多能性幹細胞を誘導する新規の化合物組成物の提供。【解決手段】ａ）特定の塩基配列、またはその塩基配列に対して１～３個の塩基が欠失、置換もしくは付加された塩基配列、を含む、１本鎖または２本鎖のポリヌクレオチド、ｂ）異なる特定の塩基配列、またはその塩基配列に対して１～３個の塩基が欠失、置換もしくは付加された塩基配列、を含む、１本鎖または２本鎖のポリヌクレオチド、ｃ）更に異なる特定の塩基配列、またはその塩基配列に対して１～３個の塩基が欠失、置換もしくは付加された塩基配列、を含む、１本鎖または２本鎖のポリヌクレオチド、からなる群から選ばれる１種以上の１本鎖または２本鎖のポリヌクレオチドを含有し、細胞を多能性幹細胞へ誘導する、多能性幹細胞誘導剤。【選択図】図６Ｃ
