PROBLEM TO BE SOLVED: To provide a method for treating or preventing diseases related to autotaxin that is characterized by administrating a compound having an inhibitory action on autotaxin.SOLUTION: A compound represented by formula (I), pharmaceuticals comprising the compound as an active ingredient and a method for treating or preventing diseases related to autotaxin by administrating the compound are provided. (R1 is a 4- to 6-membered aromatic carbocyclic group having a substituent R2, R3, R4a and R4b are each independently H, a substituted/unsubstituted alkyl, a substituted/unsubstituted alkenyl, a substituted/unsubstituted alkynyl, a substituted/unsubstituted nonaromatic carbocyclic group, a substituted/unsubstituted aromatic carbocyclic group, a substituted/unsubstituted nonaromatic heterocyclic group or a substituted/unsubstituted aromatic heterocyclic group, or the like)SELECTED DRAWING: NoneCOPYRIGHT: (C)2016,JPO&INPIT【課題】オートタキシン阻害作用を有する化合物を投与することを特徴とする、オートタキシンが関与する疾患の治療または予防方法の提供。【解決手段】式(I)で示される化合物、該化合物を有効成分とする医薬、及び該化合物を投与する、オートタキシンが関与する疾患の治療または予防方法。(R1は置換基を有する4~6員の芳香族炭素環基;R2、R3、R4a及びR4bは各々独立にH、置換/非置換のアルキル、置換/非置換のアルケニル、置換/非置換のアルキニル、置換/非置換の非芳香族炭素環式基、置換/非置換の芳香族炭素環式基、置換/非置換の非芳香族複素環式基又は置換/非置換の芳香族複素環式基等)【選択図】なし