Delfina Maria Mazzuca Siroen;Craig Hasilo;Simon Shohet;Philip Michael Toleikis;Justin Leushner;Daniel Nicholas Haworth
发明人:
Craig Hasilo,Justin Leushner,Daniel Nicholas Haworth,Simon Shohet,Philip Michael Toleikis,Delfina Maria Mazzuca Siroen
申请号：
US13393038
公开号：
US20120245705A1
申请日:
2010.08.27
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Devices and methods for transplanting cells in a host body are described. The cell comprises a porous scaffold that allows ingrowth of vascular and connective tissues, a plug or plug system configured for placement within the porous scaffold, and a seal configured to enclose a proximal opening in the porous scaffold. The device may further comprise a cell delivery device for delivering cells into the porous scaffold. The method of cell transplantation comprises a two step process. The device is incubated in the host body to form a vascularized collagen matrix around a plug positioned within the porous scaffold. The plug is then retracted from the porous scaffold, and cells are delivered into the vascularized space created within the porous scaffold.
