Hasilo, Craig,Leushner, Justin,Haworth, Daniel Nicholas,Shohet, Simon,Toleikis, Philip Michael,Siroen, Delfina Maria Mazzuca
申请号:
AU2010286531
公开号:
AU2010286531B2
申请日:
2010.08.27
申请国别(地区):
AU
年份:
2014
代理人:
摘要:
Devices and methods for transplanting cells in a host body are described. The cell comprises a porous scaffold that allows ingrowth of vascular and connective tissues, a plug or plug system configured for placement within the porous scaffold, and a seal configured to enclose a proximal opening in the porous scaffold. The device may further comprise a cell delivery device for delivering cells into the porous scaffold. The method of cell transplantation comprises a two step process. The device is incubated in the host body to form a vascularized collagen matrix around a plug positioned within the porous scaffold. The plug is then retracted from the porous scaffold, and cells are delivered into the vascularized space created within the porous scaffold.