Craig Hasilo,Justin Leushner,Daniel Nicholas Haworth,Simon Shohet,Philip Michael Toleikis,Delfina Maria Mazzuca Siroen
申请号：
US14993416
公开号：
US10034963B2
申请日:
2016.01.12
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Devices and methods for transplanting cells in a host body are described. The cell comprises a porous scaffold that allows ingrowth of vascular and connective tissues, a plug or plug system configured for placement within the porous scaffold, and a seal configured to enclose a proximal opening in the porous scaffold. The device may further comprise a cell delivery device for delivering cells into the porous scaffold. The method of cell transplantation comprises a two step process. The device is incubated in the host body to form a vascularized collagen matrix around a plug positioned within the porous scaffold. The plug is then retracted from the porous scaffold, and cells are delivered into the vascularized space created within the porous scaffold.
