Refers to a compound of formula I, where X is n, CH r1 is C1 - C3 Fluorinated Alkyl, alkoxy C1 - C4 methoxy (alkoxy optionally fluorinated c2-c4) pirrolilo, among others R2 is H, Methyl, Amine, Fluorine.Preferred compounds are: 4 - (3 - [6 - (1H - imidazol-1-yl) pyridin-3-yl] methyl} - 4.4 - dimethyl - 5-oxo-2 - tioxoimidazolidin - 1 - il) - 2 - (trifluoromethyl) benzonitrile 4 - (4,4 - dimethyl - 3 - {[2 - methyl - 5 - (trifluoromethyl) pyridin-3-yl] methyl} - 5-oxo-2 - tioxoimidazolidin - 1 - il) - 2 - (4 - (trifluoromethyl) benzonitrile 4Dimethyl - 5 - 4 - 3 - oxo - [6 - (2 - Oxoimidazolidin - 1 - il) pyridin-3-yl] methyl} - 2 - tioxoimidazolidin - 1 - il) - 2 - (trifluoromethyl) benzonitrile among others. These compounds are useful in the treatment of cancerREFERIDA A UN COMPUESTO DE FORMULA I, DONDE X ES N, CH R1 ES ALQUILO C1-C3 FLUORADO, ALCOXI C1-C4 OPCIONALMENTE FLUORADO, METOXI-(ALCOXI C2-C4)PIRROLILO, ENTRE OTROS R2 ES H, METILO, AMINO, FLUOR. SON COMPUESTOS PREFERIDOS: 4-(3-{[6-(1H-IMIDAZOL-1-IL)PIRIDIN-3-IL]METIL}-4,4-DIMETIL-5-OXO-2-TIOXOIMIDAZOLIDIN-1-IL)-2-(TRIFLUOROMETIL)BENZONITRILO 4-(4,4-DIMETIL-3-{[2-METIL-6-(TRIFLUOROMETIL)PIRIDIN-3-IL]METIL}-5-OXO-2-TIOXOIMIDAZOLIDIN-1-IL)-2-(TRIFLUOROMETIL)BENZONITRILO 4-(4,4-DIMETIL-5-OXO-3-{[6-(2-OXOIMIDAZOLIDIN-1-IL)PIRIDIN-3-IL]METIL}-2-TIOXOIMIDAZOLIDIN-1-IL)-2-(TRIFLUOROMETIL)BENZONITRILO ENTRE OTROS. DICHOS COMPUESTOS SON UTILES EN EL TRATAMIENTO DEL CANCER
