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ФАРМАЦЕВТИЧЕСКИЕ КОМПОЗИЦИИ МОНТЕЛУКАСТА И ЛЕВОЦЕТИРИЗИНА
专利权人:
ГЛЭНМАРК ФАРМАСЬЮТИКАЛС ЛИМИТЕД (IN)
发明人:
ДХУППАД Ульхас (IN)
申请号:
RU2013107724/15
公开号:
RU2013107724A
申请日:
2013.02.21
申请国别(地区):
RU
年份:
2014
代理人:
摘要:
1. A pharmaceutical composition for oral administration comprising a) montelukast or a salt thereof in an amount of about 10.4 mg b) levocetirizine or a salt thereof in an amount of 5.0 mg, lactose monohydrate, microcrystalline cellulose, anhydrous dibasic calcium phosphate, croscarmellose sodium and gidroksipropiltsellyulozu.2. A pharmaceutical composition according to claim 1, wherein the montelukast is present in form of Montelukast natriya.3. A pharmaceutical composition according to claim 1, characterized in that levocetirizine present as levocetirizine digidrohlorida.4. A pharmaceutical composition according to any one of claims 1-3, characterized in that said composition is in the form of fixed combinations doz.5. A pharmaceutical composition according to claim 4, characterized in that said composition is in the form tabletki.6. A pharmaceutical composition according to claim 5, characterized in that said tablet is coated with film obolochkoy.7. A pharmaceutical composition according to claim 1, characterized in that the microcrystalline cellulose and anhydrous dibasic calcium phosphate are present in a weight ratio of 1: 1.8. A process for preparing a pharmaceutical composition of montelukast or a salt thereof and levocetirizine or a salt thereof, comprising the steps of: a) blending montelukast sodium, lactose monohydrate, microcrystalline cellulose, anhydrous dibasic calcium phosphate and croscarmellose sodium b) dissolving the hydroxypropyl cellulose in a solvent to form a binder solution c) granulating the mixture of step a) with a binder solution of step b) d) mixing the granules from step c) with levocetirizine dihydrochloride, croscarmellose sodium, and E rokris1. Фармацевтическая композиция для перорального введения, содержащая a) монтелукаст или его соль в количестве примерно 10,4 мг b) левоцетиризин или его соль в количестве 5,0 мг, моногидрат лактозы, микрокристаллическую целлюлозу, безводный двухосновный фосфат кальция, кроскармеллозу натрия и ги
来源网站:
中国工程科技知识中心
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http://www.ckcest.cn/home/

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