The present invention relates to use of plant exosomes for reducing the protein aggregates formed in the cells and the damage they cause to the cell. The objective of the invention is to use plant exosomes, which are reliable since they are of plant origin and not transgenic, as an alternative to the drugs used in the treatment of neurodegenerative diseases, particularly ALS. Moreover this drug can, compared to the conventional applications, provide a product with high efficacy and no side effects which can be produced in high amounts and at affordable prices due to the fact that it is plant-derived.